A&P2 Lab10 Lab 10 Blood and the Heart BIO202L Student Name: Click here to enter text. Access Code (located on the lid of your lab kit): Click here to en

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A&P2 Lab10 Lab 10 Blood and the Heart BIO202L

Student Name: Click here to enter text.

Access Code (located on the lid of your lab kit): Click here to enter text.

Pre-Lab Questions:

“1. Research the process of erythropoiesis, and explain the role erythropoietin plays. Why is this a popular “doping” drug for athletes? “

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“2. How would the hemoglobin content differ in a person living in Philadelphia (Elevation: 39 feet) compared to someone living in Denver (Elevation: 5280 feet)? Why? “

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Experiment 1: Heart Valves and Pumps Table 2: Experimental Observations

Observations (with valve) and mL H2O Displaced?

Observations (without valve) and mL H2O Displaced?

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Post-Lab Questions

“1. What happened when you pressed on the balloon stretched over the jar? What does this result represent? “

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“2. What structure in this experiment mimics a heart valve? “

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“3. How did the valve influence the experimental results? If possible, indicate the difference (in mL) in water displaced with the valve versus without the valve. Does the valve enhance the water flow, and why? “

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“4. What other organs or body systems incorporate valves? How are they used? “

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Experiment 2: Effect of Chelation Therapy on Arterial Plaque Levels

Table 3: Eggshell Observations

Day

Water Observations

4% EDTA Observations

8% EDTA Observations

1

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2

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3

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4

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5

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6

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7

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8

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9

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10

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11

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12

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13

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14

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Post-Lab Questions

“1. Describe the differences you observed between the water beaker, the 4% EDTA beaker, and the 8% EDTA beaker. “

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“2. Does the beaker without EDTA serve as a positive or negative control? How do you know?

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“3. Research and determine the composition of eggshell. State your findings below, and, indicate why this composition makes eggshell a good material for EDTA to chelate. “

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“4. EDTA is a synthetic amino acid, which the body perceives as a foreign substance. EDTA is therefore delivered to the kidneys and removed from the body in urine. Explain how this process also leads to the removal of heavy metals. “

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“5. Based on your results, do you believe chelation therapy would be an effective treatment for atherosclerosis? Support your argument with experimental evidence. “

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Experiment 3: Microscopic Anatomy of Blood

Post-Lab Questions

“1. What makes red blood cells unique, compared to other cells in the body? “

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“2. How is new blood made? “

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“3. What is the main function of platelets? “

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“4. Describe how the body stops bleeding. “

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“5. Sickle cells are named so because of their characteristic shape. What problems can this shape cause? “

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“6. Explain how the absence of a nucleus affects a red blood cell’s life span. “

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Experiment 4: Blood Typing Experiment

Table 4: Blood Typing Results

A (Blood Sample A)

B (Blood Sample B)

C (Blood Sample C)

1 (Anti-A Serum)

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2 (Anti-B Serum)

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3 (Anti-Rh Serum)

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Blood Type:

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Post-Lab Questions

“1. What determines blood type? “

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“2. What type of blood antigens are expressed if a person is blood type AB negative? “

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“3. Why doesn’t a transfusion reaction occur the first time an Rh negative patient is exposed to Rh positive blood? “ Click here to enter text.

Experiment 5: Virtual Model – The Heart Coloring Activity

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Insert screenshot of the mitral valve:

Post-Lab Questions

1. What component of the heart separates the left and right ventricles?

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Which is more superior: the arch of the aorta or the atrioventricular septum?

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What component of the heart prevents the flow of the blood from the right ventricle to the right atrium?

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Experiment 6: Sheep Heart Dissection

“Insert photo of dissected sheep heart showing at least one atrioventricular valve with your name and access code handwritten clearly in the background: “

Post-Lab Questions

1. What surprised you about the anatomy of the sheep’s heart?

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Research diseases of the heart valves. How might a valvular insufficiency affect heart function? How would valvular stenosis (tightening or less ability to open easily) affect heart function?

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